DR. BANAPPA S UNGER

Scientist E

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Dr.Banappa S Unger is a Pharmacologist trained in preclinical and clinical research. Current research focus of his group is to identify the potential traditional medicine(TM)& develop scientific evidence based herbal drug technologies for chronic inflammatory and metabolic disorders (IBD, obesity, and drug induced metabolic &liver disorders). His research interest includeelucidation of “Shodhana” a processes of TM practice for detoxification/purification of drugs,Pharmaco-Toxico-Metabonomics of traditional medicine and elucidation of “Metabolic memory” a plausible underlying process of diabetic vascular complication for its prevention/reversal.He is also interested in developing/adopting an alternate animal model of human diseases; Zebrafish based assay system, a popular upcoming vertebrate model organism,an in-vitro equivalent in-vivo system and complies with 3R principles of ethics, relatively economical and scientifically valid model for toxicological and pharmacological investigation. He is also active in HRD activities and open for research collaboration aimed at fostering the research activities for improving the public health.

Top Five publications in reputed and peer reviewed journals

1. Patil KR, Mahajan UB, Unger BS, et al. Animal Models of Inflammation for Screening of Anti-inflammatory Drugs: Implications for the Discovery and Development of Phytopharmaceuticals. Int J Mol Sci. 2019;20(18):4367. Published 2019 Sep 5. doi:10.3390/ijms20184367

2. Kanna S, Hiremath SK, Unger BS. Nephroprotective activity of Bilvādi agada in gentamicin induced nephrotoxicity in male Wistar rats. Anc Sci Life. 2015;34(3):126-129. doi:10.4103/0257-7941.157146

3. Birari L, Wagh S, Patil KR, et al. Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines [published online ahead of print, 2020 Aug 18]. Cancer Chemother Pharmacol. 2020;10.1007/s00280-020-04125-w. doi:10.1007/s00280-020-04125-w

4. Unger BS, Patil BM. Apocynin improves endothelial function and prevents the development of hypertension in fructose fed rat. Indian J Pharmacol. 2009;41(5):208-212. doi:10.4103/0253-7613.58508

5. Patil BM, Kulkarni NM, Unger BS. Elevation of systolic blood pressure in an animal model of olanzapine induced weight gain. Eur J Pharmacol. 2006;551(1-3):112-115. doi:10.1016/j.ejphar.2006.09.009

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