Scientist B

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Short Description:

I completedmy BVSc & AH degree from Bangalore Veterinary College, and MVSc&Ph.D (Animal Biotechnology) from ICAR-IVRI, Izatnagar. I was previously worked on the development of edible vaccines against FMDV andoncoviral targeted gene therapies during my master and doctoral degree research programmes respectively. I started my professional career as Research officer-II (Medical) at Bangalore Medical College& Research Centre to establish thestate level Viral Research and Diagnostic laboratory and joined ICMR as Scientist B on March 2017. Presently I am working on the validation of Traditional Medicines and their mechanism of action onselecteddiseases. I am also the member secretary of IBSC, resident veterinarian and animal house in charge of this premier institute. I am having experience in molecular biology techniques, genetic engineering, tissue culture, handling of infectious agents and laboratory animal experimentation. Ihave published many research articles in peer reviewed journals and awarded with various fellowships like ICAR-JRF (1st Rank), ICAR-SRF (1st Rank), CSIR-JRF (34th Rank), ICMR-JRF, ASRB-NET and many awards from reputed scientific societies.

Selected publications

1. Canine parvovirus NS1 protein exhibits anti-tumor activity in a mouse mammary tumor model. Gupta SK, Yadav PK, Gandham RK, Sahoo AP, Harish DR, Singh AK, Tiwari AK. (2015). Virus Res. 213:289-298.

2. Canine parvovirus NS1 induced apoptosis involves mitochondria, accumulation of reactive oxygen species and activation of caspases. Gupta SK, Sahoo AP, Rosh N, Gandham RK, Saxena L, Singh AK, Harish D R, Tiwari AK. (2016). Virus Res. 213:46-61.

3. Betulinic acid attenuates lung injury by modulation of inflammatory cytokine response in experimentally induced polymicrobial sepsis in mice. Madhu C L, Nitya N P, Jubeda B, Venkanna B, Rafia A B, Harish D R, et al. (2015). Cytokine. 71: 101–108.

4. Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis. Lingaraju MC, Pathak NN, Begum J, Balaganur V, Harish DR, Bhat RA, Ram M, Singh V, Kandasamy K, Kumar D, Kumar D, Tandan SK. (2015). Eur J Pharm Sci. 70:12-21.

5. Canine Parvovirus Type 2a (CPV-2a)-Induced Apoptosis in MDCK Involves Both Extrinsic and Intrinsic Pathways. JuwarDoley, LakshyaVeerSingh, G. Ravi Kumar, Aditya Prasad Sahoo, LovleenSaxena, Uttara Chaturvedi, ShikhaSaxena, Rajiv Kumar, Prafull Kumar Singh, R. S. Rajmani, LakshmanSantra, S. K. Palia, S. Tiwari, D. R. Harish et al., (2014).. ApplBiochemBiotechnol. 172(1):497-508.

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