The Phytochemistry division, established in 2008 after joining this Institute with high-end facilities such GC-MS, HPTLC, HPLC (Analytical/Preparative), GC-FID/ECD, FTIR, FC-PDA/ELSD, Solvent extractor, etc., along with other minor equipment at ICMR-National Institute of Traditional Medicine, Belagavi and is working on the chemistry of medicinal plants and formulations. The division started with chemoprofiling of medicinal and aromatic plants (MAPs) planted in the ICMR-NITM medicinal plant garden and plants from Western Ghats, North West Karnataka. The chemical constituents of 25 MAPs have been identified for the first time. Moreover, various MAPs growing in Belagavi and North West Karnataka have also been identified as chemotype(s). The extraction, isolation, purification, and characterization of active molecules/ fractions are the basic functions of this division. The division has been identifying the antidiabetic activity of the traditionally used plants and obtained some extract(s) and a fraction(s) with potent anti-hyperglycemic activity in animal models. The division is also working on the microbiome of the medicinal plant along with its biological efficacy of those extract(s) and isolated constituents and their immunomodulatory potential. The division also works on the scientific validation of folklore medicinal plants used for the management of diabetes. A patent on antidiabetic traditional medicine has been submitted to IPR unit ICMR New Delhi.
Publication and Patent:
Book Chapters: 2
Review Reports: 6
Research Articles: 106
Patent submitted: 1
Patent filled in collaboration: 2
Citation-1033; h-index-17; i10-index-35; for publications from 2008 to 2020
Top Five publications in reputed and peer reviewed journals
1. Joshi RK. GC-MS analysis of the volatile constituents of Orthosiphon pallidusRoyle, ex Benth. Nat Prod Res. 2020; 34(3): 441-4.
2. Joshi RK. Chemical disparity in the leaf essential oil of Cinnamomum zeylanicum. Flavour fragr J. 2019; 34(6):443-449.
3. Sharma S, Rasal VP, Patil PA, Joshi RK*. Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals. Nat Prod Res. 2018;32(4):468-72.
4. Joshi RK. AcoruscalamusLinn.: Phytoconstituents and bactericidal property. World J MicrobiolBiotechnol. 2016;32(10):164.
5. Joshi RK. Chemical constituents and antibacterial property of the essential oil of the roots of Cyathocline purpurea. J Ethnopharmacol. 2013;145(2):621-5.
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